Jogos de 18 de fevereiro de 2021

Fim Dynamo Kyiv 1 1×1 Club Brugge KV 1 Fim Wolfsberger AC 1 1×4 Tottenham 4 Fim Real Sociedad 0 0×4 Manchester United 4 Fim FK Crvena Zvezda 2 2×2 AC Milan 2 Fim Slavia Praha 0 0×0 Leicester 0 Fim SC Braga 0 0×2 AS Roma 2 Fim Krasnodar 2 2×3 Dinamo Zagreb 3 Fim BSC Young Boys 4 4×3 Bayer Leverkusen 3 Fim Olympiakos Piraeus 4 4×2 PSV Eindhoven 2 Fim Benfica 1 1×1 Arsenal 1 Fim Antwerp 3 3×4 Rangers 4 Fim Red Bull Salzburg 0 0×2 Villarreal 2 Fim Molde 3 3×3 1899 Hoffenheim 3 Fim Granada CF 2 2×0 Napoli 0 Fim Maccabi Tel Aviv 0 0×2 Shakhtar Donetsk 2 Fim Lille 1 1×2 Ajax 2

Fim Al-Faisaly FC 2 2×0 Dhamk 0 Fim Al Taawon 1 1×2 Al-Ittihad FC 2 Fim Al-Qadisiyah FC 1 1×0 Al-Nassr 0 Fim Al-Hilal Saudi FC 3 3×1 Al-Ettifaq 1